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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL4
All Species:
30.91
Human Site:
T219
Identified Species:
48.57
UniProt:
Q8WUA2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA2
NP_624311.1
492
57225
T219
K
A
E
K
E
A
K
T
Q
A
I
L
L
E
M
Chimpanzee
Pan troglodytes
XP_527529
607
69328
T334
K
A
E
K
E
A
K
T
Q
A
I
L
L
E
M
Rhesus Macaque
Macaca mulatta
XP_001084421
492
57172
T219
K
A
E
K
E
A
K
T
Q
A
I
L
L
E
M
Dog
Lupus familis
XP_541147
492
57155
T219
K
A
E
K
E
A
K
T
Q
A
I
L
L
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXG3
492
57212
T219
K
A
E
K
E
A
K
T
Q
A
I
L
L
E
M
Rat
Rattus norvegicus
NP_001101927
357
40656
G127
D
G
V
H
T
V
F
G
E
V
T
E
G
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506397
487
56623
T215
M
A
E
K
E
A
K
T
Q
A
I
L
L
E
M
Chicken
Gallus gallus
XP_419663
478
55881
T219
Q
A
E
K
E
A
K
T
R
A
I
L
L
E
M
Frog
Xenopus laevis
Q6GLX7
477
54856
H232
R
G
K
S
K
S
S
H
D
L
L
K
D
D
P
Zebra Danio
Brachydanio rerio
NP_001121802
454
52864
T219
I
K
D
K
E
A
K
T
Q
A
I
L
L
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651291
653
75452
A219
L
A
E
R
E
A
K
A
R
A
T
I
L
E
I
Honey Bee
Apis mellifera
XP_001121334
512
60307
A219
Q
K
E
K
E
A
K
A
R
A
T
I
L
E
I
Nematode Worm
Caenorhab. elegans
NP_492343
427
50388
K197
D
Q
I
A
L
D
E
K
E
D
E
D
E
G
K
Sea Urchin
Strong. purpuratus
XP_001192414
536
61906
V211
G
D
L
P
D
A
D
V
K
P
P
E
N
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871A4
494
56481
A232
R
R
E
R
E
A
A
A
Q
A
L
T
L
E
M
Conservation
Percent
Protein Identity:
100
80.8
98.7
98.1
N.A.
96.7
71.9
N.A.
77
80.8
23.5
69.7
N.A.
42.4
48.6
47.5
51.1
Protein Similarity:
100
80.8
98.9
98.7
N.A.
98.1
72.3
N.A.
86.1
89
45.7
81
N.A.
55.9
65.8
65.6
65.4
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
93.3
86.6
0
80
N.A.
53.3
53.3
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
93.3
100
40
86.6
N.A.
80
80
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
7
0
80
7
20
0
74
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
7
0
7
7
7
0
7
7
0
7
7
7
7
% D
% Glu:
0
0
67
0
74
0
7
0
14
0
7
14
7
74
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
7
14
0
0
0
0
0
7
0
0
0
0
7
7
0
% G
% His:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
0
0
0
0
0
0
0
54
14
0
0
14
% I
% Lys:
34
14
7
60
7
0
67
7
7
0
0
7
0
0
7
% K
% Leu:
7
0
7
0
7
0
0
0
0
7
14
54
74
0
7
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
60
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
7
7
0
0
0
7
% P
% Gln:
14
7
0
0
0
0
0
0
54
0
0
0
0
0
0
% Q
% Arg:
14
7
0
14
0
0
0
0
20
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
0
7
7
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
7
0
0
54
0
0
20
7
0
0
0
% T
% Val:
0
0
7
0
0
7
0
7
0
7
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _